| 2019-05-10 19:00:00May 10, 2019 | Pensacola FC  | 2 - 2 |  Gulf Coast Rangers | Ashton Brosnaham Stadium | Recap | - |
| 2019-05-11 10:00:00May 11, 2019 | Gaffa FC  | 3 - 1 |  Mississippi Blues SC | Jackson Academy Stadium | Recap | - |
| 2019-05-11 19:00:00May 11, 2019 | Northshore United  | 4 - 1 |  BRSC Capitals | Wolverine Stadium | Recap | - |
| 2019-05-11 19:00:00May 11, 2019 | AFC Mobile  | 2 - 2 |  Tallahassee Soccer Club | Archbishop Lipscomb | Recap | - |
| 2019-05-11 19:00:00May 11, 2019 | Boca Knights FC  | 2 - 1 |  Louisiana Krewe FC | Bossier High School | Recap | - |
| 2019-05-11 19:00:00May 11, 2019 | Alexandria FC  | 1 - 1 |  Central Texas Lobos | Wildcat Stadium | Recap | - |
| 2019-05-11 19:00:00May 11, 2019 | LA Krewe Rush  | 5 - 1 |  Shreveport United | Clark Field | Recap | - |
| 2019-05-11 20:00:00May 11, 2019 | Motagua New Orleans  | 0 - 3 |  FC New Orleans | Pan American Stadium | Recap | - |
| 2019-05-15 18:00:00May 15, 2019 | Hattiesburg FC  | 1 - 0 |  Port City FC | Crusader Field | Recap | - |
| 2019-05-18 16:00:00May 18, 2019 | Mississippi Blues SC | 0 - 3 | Motagua New Orleans | Harper Davis Field | Recap | - |
| 2019-05-18 18:00:00May 18, 2019 | Tallahassee Soccer Club | 1 - 2 | Gulf Coast Rangers | Florida State Sports Club Fields | Recap | - |
| 2019-05-18 19:00:00May 18, 2019 | BRSC Capitals | 0 - 3 | FC New Orleans | Olympia Stadium | Recap | - |
| 2019-05-18 19:00:00May 18, 2019 | Northshore United | 2 - 1 | Gaffa FC | Wolverine Stadium | Recap | - |
| 2019-05-18 19:00:00May 18, 2019 | Hattiesburg FC | 0 - 3 | AFC Mobile | Crusader Field | Recap | - |
| 2019-05-18 19:00:00May 18, 2019 | Port City FC | 3 - 1 | Pensacola FC | Herbert Wilson Stadium | Recap | - |
| 2019-05-18 19:30:00May 18, 2019 | Central Texas Lobos | 1 - 3 | Boca Knights FC | Shelton Stadium | Recap | - |
| 2019-05-18 19:45:00May 18, 2019 | LA Krewe Rush | 0 - 3 | Alexandria FC | LUS Fiber Stadium | Recap | - |
| 2019-05-19 18:00:00May 19, 2019 | Shreveport United | 1 - 1 | Louisiana Krewe FC | Messmer Stadium | Recap | - |
| 2019-05-22 19:00:00May 22, 2019 | Shreveport United | 1 - 5 | Boca Knights FC | Lee Hedges Stadium | Recap | - |
| 2019-05-23 19:00:00May 23, 2019 | FC New Orleans | 2 - 2 | Gaffa FC | Muss Bertilino Stadium | Recap | - |
| 2019-05-25 16:00:00May 25, 2019 | Tallahassee Soccer Club | 5 - 1 | Pensacola FC | Florida State Sports Club Fields | Recap | - |
| 2019-05-25 19:00:00May 25, 2019 | Mississippi Blues SC | 1 - 3 | Northshore United | Harper Davis Field | Recap | - |
| 2019-05-25 19:00:00May 25, 2019 | Louisiana Krewe FC | 3 - 1 | Alexandria FC | UL Lafayette Soccer Field | Recap | - |
| 2019-05-25 19:00:00May 25, 2019 | Motagua New Orleans | 8 - 0 | BRSC Capitals | Pan American Stadium | Recap | - |
| 2019-05-25 19:00:00May 25, 2019 | AFC Mobile | 3 - 1 | Port City FC | Archbishop Lipscomb | Recap | - |
| 2019-05-25 19:00:00May 25, 2019 | Gulf Coast Rangers | 1 - 0 | Hattiesburg FC | Fairhope Municipal Stadium | Recap | - |
| 2019-05-25 19:30:00May 25, 2019 | Central Texas Lobos | 1 - 0 | LA Krewe Rush | Shelton Stadium | Recap | - |
| 2019-05-31 19:00:00May 31, 2019 | Northshore United | 3 - 3 | FC New Orleans | Wolverine Stadium | Recap | - |
| 2019-06-01 17:00:00June 1, 2019 | Mississippi Blues SC | 3 - 0 | BRSC Capitals | Arrow Stadium | Recap | - |
| 2019-06-01 18:00:00June 1, 2019 | Hattiesburg FC | 0 - 1 | Tallahassee Soccer Club | Crusader Field | Recap | - |
| 2019-06-01 19:00:00June 1, 2019 | Alexandria FC | 10 - 0 | Shreveport United | Wildcat Stadium | Recap | - |
| 2019-06-01 19:00:00June 1, 2019 | Louisiana Krewe FC | 1 - 0 | Central Texas Lobos | UL Lafayette Soccer Field | Recap | - |
| 2019-06-01 19:00:00June 1, 2019 | Boca Knights FC | 4 - 2 | LA Krewe Rush | Bossier High School | Recap | - |
| 2019-06-01 19:00:00June 1, 2019 | Motagua New Orleans | 5 - 2 | Gaffa FC | Pan American Stadium | Recap | - |
| 2019-06-01 19:00:00June 1, 2019 | Pensacola FC | 3 - 4 | AFC Mobile | Ashton Brosnaham Stadium | Recap | - |
| 2019-06-05 19:00:00June 5, 2019 | Boca Knights FC | 0 - 3 | Alexandria FC | Bossier High School | Recap | - |
| 2019-06-05 19:00:00June 5, 2019 | Gulf Coast Rangers | 0 - 0 | Port City FC | Fairhope Municipal Stadium | Recap | - |
| 2019-06-08 18:00:00June 8, 2019 | Tallahassee Soccer Club | 3 - 1 | Port City FC | Florida State Sports Club Fields | Recap | - |
| 2019-06-08 19:00:00June 8, 2019 | Shreveport United | 0 - 4 | Central Texas Lobos | Cargill Park | Recap | - |
| 2019-06-08 19:00:00June 8, 2019 | FC New Orleans | 12 - 1 | Mississippi Blues SC | Pan American Stadium | Recap | - |
| 2019-06-08 19:00:00June 8, 2019 | BRSC Capitals | 1 - 4 | Gaffa FC | Olympia Stadium | Recap | - |
| 2019-06-08 19:00:00June 8, 2019 | LA Krewe Rush | 0 - 1 | Louisiana Krewe FC | LUS Fiber Stadium | Recap | - |
| 2019-06-08 19:00:00June 8, 2019 | AFC Mobile | 3 - 4 | Gulf Coast Rangers | Archbishop Lipscomb Stadium | Recap | - |
| 2019-06-12 19:30:00June 12, 2019 | Pensacola FC | 1 - 3 | Hattiesburg FC | Ashton Brosnaham Stadium | Recap | - |
| 2019-06-12 20:00:00June 12, 2019 | Motagua New Orleans | 2 - 3 | Northshore United | Pan American Stadium | Recap | - |
| 2019-06-15 17:00:00June 15, 2019 | BRSC Capitals | 3 - 7 | Motagua New Orleans | Olympia Stadium | Recap | - |
| 2019-06-15 19:00:00June 15, 2019 | Louisiana Krewe FC | 1 - 1 | Boca Knights FC | UL Lafayette Soccer Field | Recap | - |
| 2019-06-15 19:00:00June 15, 2019 | Shreveport United | 0 - 4 | LA Krewe Rush | Cargill Park | Recap | - |
| 2019-06-15 19:00:00June 15, 2019 | Gaffa FC | 2 - 2 | FC New Orleans | Freedom Ridge Park Stadium | Recap | - |
| 2019-06-15 19:00:00June 15, 2019 | Northshore United | 2 - 0 | Mississippi Blues SC | Wolverine Stadium | Recap | - |
| 2019-06-15 19:00:00June 15, 2019 | Tallahassee Soccer Club | 0 - 0 | AFC Mobile | Florida State Sports Club Fields | Recap | - |
| 2019-06-15 19:00:00June 15, 2019 | Port City FC | 2 - 1 | Hattiesburg FC | Herbert Wilson Stadium | Recap | - |
| 2019-06-15 19:00:00June 15, 2019 | Gulf Coast Rangers | 2 - 7 | Pensacola FC | Fairhope Municipal Stadium | Recap | - |
| 2019-06-15 19:30:00June 15, 2019 | Central Texas Lobos | 3 - 4 | Alexandria FC | Shelton Stadium | Recap | - |
| 2019-06-19 19:00:00June 19, 2019 | Alexandria FC | 1 - 0 | LA Krewe Rush | Wildcat Stadium | Recap | - |
| 2019-06-19 19:00:00June 19, 2019 | FC New Orleans | 7 - 2 | BRSC Capitals | Pan American Stadium | Recap | - |
| 2019-06-22 19:00:00June 22, 2019 | Louisiana Krewe FC | 3 - 0 | Shreveport United | UL Lafayette Soccer Field | Recap | - |
| 2019-06-22 19:00:00June 22, 2019 | Boca Knights FC | 5 - 0 | Central Texas Lobos | Bossier High School | Recap | - |
| 2019-06-22 19:00:00June 22, 2019 | Gaffa FC | 1 - 0 | Northshore United | Freedom Ridge Park Stadium | Recap | - |
| 2019-06-22 19:00:00June 22, 2019 | Motagua New Orleans | 9 - 0 | Mississippi Blues SC | Pan American Stadium | Recap | - |
| 2019-06-22 19:00:00June 22, 2019 | Gulf Coast Rangers | 0 - 2 | Tallahassee Soccer Club | Fairhope Municipal Stadium | Recap | - |
| 2019-06-22 19:00:00June 22, 2019 | Pensacola FC | 5 - 4 | Port City FC | Ashton Brosnaham Stadium | Recap | - |
| 2019-06-22 19:00:00June 22, 2019 | AFC Mobile | 2 - 1 | Hattiesburg FC | Archbishop Lipscomb Stadium | Recap | - |
| 2019-06-28 19:00:00June 28, 2019 | Alexandria FC | 2 - 6 | Louisiana Krewe FC | Wildcat Stadium | Recap | - |
| 2019-06-29 19:00:00June 29, 2019 | LA Krewe Rush | 2 - 1 | Central Texas Lobos | LUS Fiber Stadium | Recap | - |
| 2019-06-29 19:00:00June 29, 2019 | Mississippi Blues SC | 0 - 2 | Gaffa FC | Harper Davis Field | Recap | - |
| 2019-06-29 19:00:00June 29, 2019 | Boca Knights FC | 3 - 1 | Shreveport United | Bossier High School | Recap | - |
| 2019-06-29 19:00:00June 29, 2019 | Port City FC | 2 - 1 | AFC Mobile | Herbert Wilson Stadium | Recap | - |
| 2019-06-29 19:00:00June 29, 2019 | Hattiesburg FC | 2 - 2 | Gulf Coast Rangers | Crusader Field | Recap | - |
| 2019-06-29 19:00:00June 29, 2019 | Pensacola FC | 1 - 1 | Tallahassee Soccer Club | Ashton Brosnaham Stadium | Recap | - |
| 2019-06-29 20:00:00June 29, 2019 | FC New Orleans | 4 - 2 | Motagua New Orleans | Tad Gormley | Recap | - |
| 2019-07-02 19:00:00July 2, 2019 | BRSC Capitals | 0 - 1 | Northshore United | Olympia Stadium | Recap | - |
| 2019-07-06 19:00:00July 6, 2019 | LA Krewe Rush | 2 - 2 | Boca Knights FC | LUS Fiber Stadium | Recap | - |
| 2019-07-06 19:00:00July 6, 2019 | Shreveport United | 3 - 1 | Alexandria FC | Cargill Park | Recap | - |
| 2019-07-06 19:00:00July 6, 2019 | FC New Orleans | 0 - 1 | Northshore United | Pan American Stadium | Recap | - |
| 2019-07-06 19:00:00July 6, 2019 | Gaffa FC | 1 - 2 | Motagua New Orleans | Freedom Ridge Park Stadium | Recap | - |
| 2019-07-06 19:00:00July 6, 2019 | BRSC Capitals | 7 - 2 | Mississippi Blues SC | Olympia Stadium | Recap | - |
| 2019-07-06 19:00:00July 6, 2019 | Port City FC | 4 - 3 | Gulf Coast Rangers | Herbert Wilson Stadium | Recap | - |
| 2019-07-06 19:00:00July 6, 2019 | AFC Mobile | 2 - 1 | Pensacola FC | Archbishop Lipscomb Stadium | Recap | - |
| 2019-07-06 19:30:00July 6, 2019 | Central Texas Lobos | 0 - 5 | Louisiana Krewe FC | Shelton Stadium | Recap | - |
| 2019-07-06 20:00:00July 6, 2019 | Tallahassee Soccer Club | 1 - 0 | Hattiesburg FC | Florida State Sports Club Fields | Recap | - |
| 2019-07-13 19:30:00July 13, 2019 | Central Texas Lobos | 8 - 3 | Shreveport United | Shelton Stadium | Recap | - |
| 2019-07-17 18:30:00July 17, 2019 | Hattiesburg FC | 6 - 2 | Pensacola FC | Crusader Field | Recap | - |
| 2019-07-17 19:00:00July 17, 2019 | Northshore United | 1 - 3 | Motagua New Orleans | Wolverine Stadium | Recap | - |
| 2019-07-17 19:00:00July 17, 2019 | Alexandria FC | 2 - 2 | Boca Knights FC | Wildcat Stadium | Recap | - |
| 2019-07-17 19:00:00July 17, 2019 | Louisiana Krewe FC | 0 - 1 | LA Krewe Rush | UL Lafayette Soccer Field | Recap | - |
| 2019-07-17 19:00:00July 17, 2019 | Mississippi Blues SC | 0 - 6 | FC New Orleans | Arrow Stadium | Recap | - |
| 2019-07-17 19:00:00July 17, 2019 | Gulf Coast Rangers | 1 - 3 | AFC Mobile | Fairhope Municipal Stadium | Recap | - |
| 2019-07-20 19:00:00July 20, 2019 | Gaffa FC | 6 - 2 | BRSC Capitals | Freedom Ridge Park Stadium | Recap | - |
Boca Knights FC
Louisiana Krewe FC
Alexandria FC
LA Krewe Rush
Central Texas Lobos
Shreveport United
Northshore United
FC New Orleans
Motagua New Orleans
Gaffa FC
BRSC Capitals
Mississippi Blues SC
AFC Mobile
Tallahassee Soccer Club
Port City FC
Gulf Coast Rangers
Hattiesburg FC
Pensacola FC
